Raquel Real and Antonio Trabalza’s work selected for talk at Keystone Symposia in Santa Fe


Raquel Real and Antonio Trabalza are studying axon and synaptic pathology in neurons derived from human-induced pluripotent stem cells, grafted into the mouse brain for longitudinal multiphoton imaging. To model Alzheimer’s disease they use Down syndrome patient-derived neurons, due to the high incidence of early-onset Alzheimer’s disease in Down syndrome patients. The work, done in collaboration with Rick Livesey of the Department of Biochemistry and the Gurdon Institute, University of Cambridge, has been selected from a pool of highly competitive abstracts for a short talk at the Keystone Symposia Conference (Axons: From Cell Biology to Pathology) in Santa Fe, New Mexico, USA from January 24 – 27, 2016.