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PAPERSPEER REVIEW ABSTRACTS
IN BOOKS, JOURNALS AND PROCEEDINGS -
PAPERSIN BOOKS, JOURNALS AND PROCEEDINGSPEER REVIEW ABSTRACTS
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PAPERSIN BOOKS, JOURNALS AND PROCEEDINGSPEER REVIEW ABSTRACTS
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PAPERSIN BOOKS, JOURNALS AND PROCEEDINGSPEER REVIEW ABSTRACTS
2022
Preprint / Submitted / In Preparation
Impaired axon regeneration and heightened synaptic dynamics in the injured aged mouse cortex.
Bass, C., Clopath, C., Bharath, A. A., De Paola, V.
(2022, in preparation)
Laser mediated single neuron transection in the living mammalian brain.
Huang, L, Canty, A. J., De Paola, V.
Journal of Visualized Experiments (2022, invited submission, in preparation)
Rapid experience-dependent structural plasticity of axonal boutons in the adult barrel cortex in vivo.
Huang, L., Grillo, F., Song, S., Holtmaat, A., Wilbrecht, L., Adalbert, A. N., Nogradi, A., Ruivo, L., Knott, G., Ferretti, V., De Paola, V.
(2022, in preparation)
2022
Cohesin-dependence of neuronal gene expression relates to chromatin loop length.
Calderon, L., Weiss, F. D., Beagan, J. A., Oliveira, M. S., Georgieva, R., Wang, Y.-F., Carroll, T. S., Dharmalingam, G., Gong, W., Tossell, K., de Paola, V., Whilding, C., Ungless, M. A., Fisher, A. G., Phillips-Cremins, J. E., Merkenschlager, M.
ELife 11:e76539 (2022).
2021 – 2017
2021
Pharmacological ablation of astrocytes reduces Aβ degradation and synaptic connectivity in an ex vivo model of Alzheimer’s disease.
Davis, N., Mota, B. C., Stead, L., Palmer, E. O. C., Lombardero, L., Rodríguez-Puertas, R., de Paola, V., Barnes, S. J., Sastre, M.
Journal of Neuroinflammation 18, 73.
2020
In vivo imaging of injured cortical axons reveals a rapid onset form of Wallerian degeneration.
Canty, A. J., Jackson, J. S., Huang, L., Trabalza, A., Bass, C., Little, G., Tortora, M., Khan, S., De Paola, V.
BMC Biology 18, 170 (2020).
2019
Image synthesis with a convolutional capsule generative adversarial network
Bass, C., Dai, T., Billot, B., Arulkumaran, K., Creswell, A., Clopath, C., De Paola, V., Bharath, A. A.
Proceedings of Machine Learning Research 102, 39-62 (2019).
Deep reinforcement learning for subpixel neural tracking
Dai, T., Dubois, M., Arulkumaran, K., Campbell, J., Bass, C., Billot, B., Uslu, F., de Paola, V., Clopath, C., Bharath, A. A.
Proceedings of Machine Learning Research 102, 130-150 (2019).
2018
The effects of haloperidol on microglial morphology and translocator protein levels: An in vivo study in rats using an automated cell evaluation pipeline.
Bloomfield, P. S., Bonsall, D., Wells, L., Dormann, D., Howes, O.*, De Paola, V.*
Journal of Psychopharmacology 32, 1264-1272 (2018).
*Joint senior authors
The effects of aging on neuropil structure in mouse somatosensory cortex—A 3D electron microscopy analysis of layer 1.
Calì, C., Wawrzyniak, M., Becker, C., Maco, B., Cantoni, M., Jorstad, A., Nigro, B., Grillo, F., De Paola, V., Fua, P., Knott, G. W.
PLoS One 12, e0198131 (2018).
In vivo modeling of human neuron dynamics and Down syndrome
Real, R.*, Peter, M.*, Trabalza, A.*, Khan, S., Smith, M. A., Dopp, J., Barnes, S. J., Momoh, A., Strano, A., Volpi, E., Knott, G., Livesey, F. J.†, De Paola, V.†
Science 362, eaau1810 (2018).
*Joint first authors, †Corresponding authors
Neuron Spotlight | F1000Prime | Nature Reviews Neurology Research Highlight | MRC London Institute of Medical Science News | MRC News | Spectrum | Adnkronos (Italian) | Público (Portuguese) | Imperial College London Podcast | Imperial College London News |
2017
In vivo imaging of CNS injury and disease.
Akassoglou, K.*, Merlini, M., Rafalski, V. A., Real, R., Liang, L.*, Jin, Y., Dougherty, S. E., De Paola, V.*, Linden, D. J.*, Misgeld, T.*, Zheng, B.*
The Journal of Neuroscience 37, 10808-10816 (2017).
*Contributed equally to work
Cover article |
Detection of axonal synapses in 3D two-photon images.
Bass, C., Helkkula, P., De Paola, V., Clopath, C., Bharath, A. A.
PLoS One 12, e0183309 (2017).
Open source high content analysis utilizing automated fluorescence lifetime imaging microscopy.
Görlitz, F., Kelly, D. J., Warren, S. C., Alibhai, D., West, L., Kumar, S., Alexandrov, Y., Munro, I., Garcia, E., McGinty, J., Talbot, C., Serwa, R. A., Thinon, E., de Paola, V., Murray, E. J., Stuhmeier, F., Neil, M. A., Tate, E. W., Dunsby, C., French, P. M.
Journal of Visualized Experiments 119, e55119 (2017).
2016 – 2012
2016
Microglial activity in people at ultra high risk of psychosis and in schizophrenia: an [11C]PBR28 PET brain imaging study.
Bloomfield, P. S., Selvaraj, S., Veronese, M., Rizzo, G., Bertoldo, A., Owen, D. R., Bloomfield, M. A. P., Bonoldi, I., Kalk, N., Turkheimer, F., McGuire, P., de Paola, V.*, Howes, O. D.* (2016).
The American Journal of Psychiatry 173, 44-52 (2016).
*Joint senior authors
Cover article | Editor Spotlight | Editorial | BBC News | Imperial College London News | MRC News | New Scientist |
In vivo visualization of single axons and synaptic remodeling in normal and pathological conditions.
Grillo, F., Canty, A. J., Bloomfield, P. S., De Paola, V.
In: Axons and Brain Architecture. ed. Rockland, K. S., pp. 221-243. Academic Press (2016).
EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells.
Krusche, B., Ottone, C., Clements, M. P., Johnstone, E. R., Goetsch, K., Lieven, H., Mota, S. G., Singh, P., Khadayate, S., Ashraf, A., Davies, T., Pollard, S. M., De Paola, V., Roncaroli, F., Martinez-Torrecuadrada, J., Bertone, P., Parrinello, S.
eLife 5, e14845 (2016).
EPBscore: a novel method for computer-assisted analysis of axonal structure and dynamics.
Song, S., Grillo, F. W., Xi, J., Ferretti, V., Gao, G., De Paola, V.
Neuroinformatics 14, 121-127 (2016).
2015
Removing synaptic breaks on learning.
Grillo, F. W., West, L., De Paola, V.
Nature Neuroscience 18, 1062-1064 (2015).
Laser-mediated microlesions in the mouse neocortex to investigate neuronal degeneration and regeneration.
Jackson, J., Canty, A. J., Huang, L., De Paola, V.
Current Protocols in Neuroscience 73, 2.24.1-2.24.17 (2015).
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus.
Johnson, M. R., Behmoaras, J., Bottolo, L., Krishnan, M. L., Pernhorst, K., Santoscoy, P. L. M., Rossetti, T., Speed, D., Srivastava, P. K., Chadeau-Hyam, M., Hajji, N., Dabrowska, A., Rotival, M., Razzaghi, B., Kovac, S., Wanisch, K., Grillo, F. W., Slaviero, A., Langley, S. R., Shkura, K., Roncon, P. De, T., Mattheisen, M., Niehusmann, P., O’Brien, T. J., Petrovski, S., von Lehe, M., Hoffmann, P., Eriksson, J., Coffey, A. J., Cichon, S., Walker, M., Simonato, M., Danis, B., Mazzuferi, M., Foerch, P., Schoch, S., De Paola, V., Kaminski, R. M., Cunliffe, V. T., Becker, A. J., Petretto, E.
Nature Communications 6, 6301 (2015).
F1000Prime |
Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson’s disease.
Pienaar, I. S., Gartside, S. E., Sharma, P., De Paola, V., Gretenkord, S., Withers, D., Elson, J. L., Dexter, D. T.
Molecular Neurodegeneration 10, 47 (2015).
2013
In vivo single branch axotomy induces GAP-43-dependent sprouting and synaptic remodeling in cerebellar cortex.
Allegra-Mascaro, A. L., Cesare, P., Sacconi, L., Grasselli, G., Mandolesi, G., Maco, B., Knott, G., Huang, L, De Paola, V., Strata, P., Pavone, F. S.
Proceedings of the National Academy of Sciences of the United States of America 110, 10824-10829 (2013).
In-vivo single neuron axotomy triggers axon regeneration to restore synaptic density in specific cortical circuits.
Canty, A. J., Huang, L., Jackson, J..S., Little, G. E., Knott, G., Maco, B., De Paola, V.
Nature Communications 4, 2308 (2013).
Nature Research Highlights |
Synaptic elimination and protection after minimal injury depend on cell type and their prelesion structural dynamics in the adult cerebral cortex.
Canty, A. J., Teles-Grilo Ruivo, L., Nesarajah, C., Song, S., Jackson, J. S., Little, G. E., De Paola, V.
The Journal of Neuroscience 33, 10374-10383 (2013).
Increased axonal bouton dynamics in the aging mouse cortex.
Grillo, F. W., Song, S., Teles-Grilo Ruivo, L. M., Huang, L., Ge, G., Knott, G. W., Maco, B., Ferretti, V., Thompson, D., Little, G. E., De Paola, V.
Proceedings of the National Academy of Sciences of the United States of America 110, E1514-E1523 (2013).
Nature Research Highlights | F1000Prime |
2012
Activin induces cortical interneuron identity and differentiation in embryonic stem cell-derived telencephalic neural precursors.
Cambray, S., Arber, C., Little, G., Dougalis, A. G., de Paola, V., Ungless, M. A., Li, M., Rodríguez, T. A.
Nature Communications 3, 841 (2012).
F1000Prime |
Imaging neocortical neurons through a chronic cranial window.
Holtmaat. A., de Paola, V., Wilbrecht, L., Trachtenberg, J. T., Svoboda, K., Portera-Cailliau, C.
Cold Spring Harbor Protocols June, 694-701 (2012).
2011 – 2007
2011
The DIADEM data sets: representative light microscopy images of neuronal morphology to advance automation of digital reconstructions.
Brown, K. M., Barrionuevo, G., Canty, A. J., De Paola, V., Hirsch, J. A., Jefferis, G. S. X. E., Lu, J. L., Snippe, M., Sugihara, I., Ascoli, G. A.
Neuroinformatics 9, 143-157 (2011).
Axonal reconstructions going live.
Canty, A. J., De Paola, V.
Neuroinformatics 9, 129-131 (2011).
2009
Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window.
Holtmaat, A.*, Bonhoeffer, T., Chow, D. K., Chuckowree, J., De Paola, V.*, Hofer, S. B., Hübener, M.*, Keck, T., Knott, G.*, Lee, W.-C. A., Mostany, R., Mrsic-Flogel, T. D., Nedivi, E.*, Portera-Cailliau, C.*, Svoboda, K., Trachtenberg, J. T.*, Wilbrecht, L.
Nature Protocols 4, 1128-1144 (2009).
Except for first author, authors listed alphabetically; *Corresponding authors
Dendritic spine morphology determines membrane-associated protein exchange between dendritic shafts and spine heads.
Hugel, S., Abegg, M., de Paola, V., Caroni, P., Gähwiler, B. H., McKinney, R. A.
Cerebral Cortex 19, 697-702 (2009).
2008
Imaging of experience-dependent structural plasticity in the mouse neocortex in vivo.
Holtmaat, A., De Paola, V., Wilbrecht, L., Knott, G. W.
Behavioural Brain Research 192, 20-25 (2008).
Imaging of experience-dependent structural plasticity in the mouse neocortex in vivo.
Holtmaat, A., De Paola, V., Wilbrecht, L., Knott, G.
In: Synaptic Plasticity and the Mechanism of Alzheimer’s Disease. ed. Selko, D. J., Triller, A. and Christen, Y., pp. 37-49. Berlin, Heidelberg: Springer-Verlag (2008).
2006 – 2002
2006
Cell type-specific structural plasticity of axonal branches and boutons in the adult neocortex.
De Paola, V., Holtmaat, A., Knott, G., Song, S., Wilbrecht, L., Caroni, P., Svoboda, K.
Neuron 49, 861-875 (2006).
Neuron News and Views | F1000Prime |
Long-term live imaging of neuronal circuits in organotypic hippocampal slice cultures.
Gogolla, N., Galimberti, I., DePaola, V., Caroni, P.
Nature Protocols 1, 1223-1226 (2006).
Preparation of organotypic hippocampal slice cultures for long-term live imaging.
Gogolla, N., Galimberti, I., DePaola, V., Caroni, P.
Nature Protocols 1, 1165-1171 (2006).
Staining protocol for organotypic hippocampal slice cultures.
Gogolla, N., Galimberti, I., DePaola, V., Caroni, P.
Nature Protocols 1, 2452-2456 (2006).
2005
Diverse modes of axon elaboration in the developing neocortex.
Portera-Cailliau, C., Weimer, R. M., De Paola, V., Caroni, P., Svoboda, K.
PLoS Biology 3, e272 (2005).
Nature Reviews Neuroscience Research Highlight | F1000Prime |
Glutamate induces the rapid formation of spine head protrusions in hippocampal slice cultures.
Richards, D. A., Mateos, J. M., Hugel, S., de Paola, V., Caroni, P., Gähwiler, B. H., McKinney, R. A.
Proceedings of the National Academy of Sciences of the United States of America 102, 6166-6171 (2005).
F1000Prime |
2004
AMPA-receptor activation regulates the diffusion of a membrane marker in parallel with dendritic spine motility in the mouse hippocampus.
Richards, D. A., De Paola, V., Caroni, P., Gähwiler, B. H., McKinney, R. A.
The Journal of Physiology 558, 503-512 (2004).
The Journal of Physiology Perspectives |
2003
Presynaptic terminal dynamics in the hippocampus.
De Paola, V.
PhD Thesis. University of Basel, Faculty of Science (2003).
AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks.
De Paola, V., Arber, S., Caroni, P.
Nature Neuroscience 6, 491-500 (2003).
Cover article | Trends in Neurosciences Research Focus |
2002
ETS gene Pea3 controls the central position and terminal arborization of specific motor neuron pools.
Livet, J., Sigrist, M., Stroebel, S., De Paola, V., Price, S. R., Henderson, C. E., Jessell, T. M., Arber, S.
Neuron 35, 877-892 (2002).
Cover article | Neuron Minireview |
2021 – 2018
2021
In vivo modelling of human axon degeneration and regeneration.
Khan, S.*, Tortora, M.*, O’Brien, N., Nizetic, D., De Paola, V.
Society for Neuroscience (SfN) Global Connectome: A Virtual Event, 11 – 13 January 2021.
*Contributed equally to work
2020
In vivo modelling of human axon degeneration and regeneration.
Khan, S.*, Tortora, M.*, O’Brien, N., Nizetic, D., De Paola, V.
Federation of European Neuroscience Societies (FENS) 2020 Virtual Forum, 11 – 15 July 2020.
*Contributed equally to work
New in vivo models of human axon degeneration in neurodegenerative diseases.
Tortora, M.*, Khan, S.*, O’Brien,, N., Alic, I., Nizetic, D., De Paola, V.
Imperial – Alzheimer’s Research UK Dementia Symposium, 16 December 2020, London, United Kingdom.
*Contributed equally to work
2019
In vivo modeling of human neuron dynamics and Down syndrome.
De Paola, V.
The 12th UK-Korea Neuroscience Symposium, 12-13 August 2019, Francis Crick Institute, London, United Kingdom.
Functional iPSC-derived human cortical circuitry assembled in vivo.
Real, R., Peter, M., Trabalza, A, Khan, S., Smith, M. A., Dopp, J., Barnes, S. J., Alessio, S., Emanuela, V., Knott, G., Livesey, F., De Paola, V.
“Circuits Development & Axon Regeneration” – 3rd AXON Meeting, 11 – 13 September 2019, Alicante, Spain.
2018
Functional iPSC-derived human cortical circuitry assembled in vivo.
Real, R., Trabalza, A., Peter, M., Bass, C., Khan, S., Smith, M., Dopp, S., Barnes, M., Smith, M. Knott, G., Livesey, F., De Paola, V.
11th Federation of European Neuroscience Societies (FENS) Forum of European Neuroscience, 7 – 11 July 2018, Berlin, Germany.
2017 – 2013
2017
Neuronal network dysfunction in a new humanised mouse model of Down syndrome.
Real, R.*, Trabalza, A.*, Peter, M., Bachar, C., Smith, M., Knott, G., Livesey, F., De Paola, V.
Alzeheimer’s Research UK (ARUK) Imperial College London (ICL) Symposium, 2017, London, United Kingdom.
(Selected for oral presentation)
*Contributed equally to work
Neuronal network dysfunction in a new humanised mouse model of Down syndrome.
Real, R.*, Trabalza, A.*, Peter, M., Bachar, C., Smith, M., Knott, G., Livesey, F., De Paola, V.
6th Cambridge Neuroscience Symposium – Neural Networks in Health & Disease, 7 – 8 September 2017, Cambridge, United Kingdom.
(Best poster prize winner)
*Contributed equally to work
Gallery
2016
Long-term imaging of axon growth and calcium activity in human iPSC-derived neurons from healthy and Down syndrome donors grafted in the adult mouse brain.
Real, R., Trabalza, A., Peter, M., Smith, M., Knott, G., Livesey, F., De Paola, V.
Keystone Symposium on Molecular and Cellular Biology, 24 – 26 January 2016, Santa Fe, California, USA.
(Selected for oral presentation)
Long-term imaging of axon growth and calcium activity in human iPSC-derived neurons from healthy and Down syndrome donors grafted in the adult mouse brain.
Real, R., Trabalza A., Peter, M., Smith, M., Knott, G., Livesey, F., De Paola, V.
10th Federation of European Neuroscience Societies (FENS) Forum of Neuroscience, 2 – 6 July 2016, Copenhagen, Denmark.
Longitudinal 2-photon imaging reveals rapid synaptic remodelling on spontaneously active human iPSC-derived neurons transplanted in vivo.
Trabalza, A., Real, R., Peter, M., Knott, G., Livesey, F., De Paola, V.
Cold Spring Harbor Asia Conference on Probing Neural Networks with Light: Imaging Structure & Function in the Living Brain, 17 – 21 October 2016, Suzhou, China.
2015
Image analysis tools for studying axonal and presynaptic bouton dynamics in the living brain.
Bachar, C., De Paola, V.
Neural Engineering Transformative Technologies (NETT) Conference, 21-23 September 2015, Barcelona, Spain.
Translational investigation of microglia and antipsychotic medication.
Bloomfield, P. S., Selvaraj, S., Bonoldi, I., Veronese, Owen, D., Kalk, N., Bloomfield, M., Turkheimer, F., McGuire, P., de Paola, V., Howes, O.
XII European Meeting on Glial Cells in Health and Disease, 15 – 18 July 2015, Bilboa, Spain.
(Published in Glia 63, E315, 2015.)
The effects of antipsychotic treatment on brain volume, inflammation and glutamate signaling genes.
Bloomfield, P., Howes, O. D., De Paola, V.
15th International Congress on Schizophrenia Research (ICOSR), 28 March – 01 April 2015, Colorado Springs, USA .
(Published in Schizophrenia Bulletin 41, Supplement 1, 2015.)
Microglial activity in people at ultra high risk of psychosis and in schizophrenia: An [11C]PBR28 PET brain imaging study.
Selvaraj, S., Bloomfield, P., Veronese, M., Rizzo, G., Bertoldo, A., Owen, D. R., Bloomfield, M,, Bonoldi, I., Kalk, N., Federico, T., McGuire, P., De Paola, V., Howes, O. (2015).
70th Annual Scientific Meeting of the Society of Biological Psychiatry on Stress, Emotion, Neurodevelopment and Psychopathology, 14 – 16 May 2015, Toronto, Canada.
(Published in Biological Psychiatry 77, Supplement, S142-S286, 2015.)
Microglia, psychosis and medication; a translational investigation.
Selvaraj, S., Bonoldi, I., Veronese, M., Rizzo, G., Owen, D., Kalk, N., Bloomfield, M. A. P., Turkheimer, F., McGuire, P., De Paola, V.*, Howes, O. D.*
British Association for Psychopharmacology (BAP) 2015 Summer Meeting, 26 – 29 July 2015, Bristol, United Kingdom.
(Selected for oral presentation)
*Joint senior authors
2014
Translational investigation of microglia in psychosis: the influence of antipsychotic medication.
Bloomfield, P., De Paola, V., Howes, O.
BBSRC & Biochemical Society “Sparking Impact” Meeting, 16 – 17 December 2014, London, United Kingdom.
(Selected for oral presentation)
The effects of antipsychotic medication on cortical inflammation
Bloomfield, P. S., West, L. A., Howes, O. D.*, de Paola, V.* (2014).
British Association for Psychopharmacology (BAP) 2014 Summer Meeting, 20 – 23 July 2014, Cambridge, United Kingdom.
*Joint senior authors
The effects of antipsychotic medication on cortical and peripheral inflammation.
Bloomfield, P., West, L. Howes, O.*, De Paola, V.*
27th ECNP Congress of Applied and Translational Neuroscience, 18 – 21 October 2014, Berlin, Germany.
(Published in European Neuropsychopharmacology 24, Supplement 2, S516, 2014.)
*Joint senior authors
A novel form of rapid onset cortical axon degeneration regulated by a NAD+-dependent pathway.
Canty, A.*, Jackson, J.*, Huang, L., Little, G., De Paola, V.
Neurotrauma Meeting, 2014, Australia.
*Contributed equally to work
A DREADD approach for acute stimulation of cholinergic neurons of the pedunculopontine nucleus reverses Parkinsonism in the lactacystin model of Parkinson’s disease.
Pienaar, I. S., Sharma, P., Elson, J. L., De Paola, V., Dexter, D. T.
MDS 18th International Congress of Parkinson’s Disease and Movement Disorders, Stockholm, Sweden, 8 – 12 June, 2014.
(Published in Movement Disorders 29, Supplement 1, 381, 2014.)
Molecular mechanisms of axon and synaptic remodelling in the adult injured brain.
Real, R., De Paola, V.
MRC Quinquennial Review (QQR) site visit, 2014, London, United Kingdom.
A semi-automated program for axonal reconstructions from time-lapse 2-photon images.
Yang, Z., Wang, Q., Gao, G., Li, X., Grillo, F., Ferretti, V., De Paola, V., Song, S.
INCF Neuroinformatics 2014, 25-27 August 2014, Leiden, Germany.
2013
In vivo two-photon imaging of climbing fibers plasticity after laser axotomy.
Allegra Mascaro, A. L., Cesare, P., Sacconi, L., Grasselli, G., Mandolesi, G., Maco, B., Knott, G. W., De Paola, V., Strata, P., Pavone, F. S.
European Conferences on Biomedical Optics (ECBO) 12 – 16 May 2013, Munich, Germany.
(Published in Proceedings of SPIE 8804, 880407, 2013.)
In vivo reactive neural plasticity investigation by means of correlative two photon : electron microscopy.
Allegra Mascaro, A. L., Cesare, P., Sacconi, L., Grasselli, G., Mandolesi, G., Maco, B., Knott, G., Huang, L., De Paola, V., Strata, P., Pavone, F. S.
International Society for Optics and Photonics (SPIE) – Multiphoton Microscopy in the Biomedical Sciences XIII, 2 February 2013, San Francisco, USA.
(Published in Proceedings of SPIE 8588, 85881A, 2013.)
Cortical effects of chronic haloperidol administration in rats.
Bloomfield, P., Howes, O.*, De Paola, V.*
British Association for Psychopharmacology (BAP), 2013, Harrogate, United Kingdom.
*Joint senior authors
Chronic administration of haloperidol in rats and its effect on microglial cell density and whole brain weight and volume.
Bloomfield, P. S., Howes, O. D., de Paola, V.
ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe, 7 – 10 March 2013, Nice, France.
(Published in European Neuropsychopharmacology 23, Supplement 1, S20-S21, 2013.)
2012 – 2008
2012
Climbing fibers reactive plasticity after laser axotomy.
Allegra Mascaro, A. L.*, Cesare, P.*, Sacconi, L.*, Grasselli,G., De Paola, V., Knott, G. W., Strata, P., Pavone, F. S.
Society for Neuroscience (SfN) 2012, New Orleans, USA.
(Selected for oral presentation)
*Contributed equally to work
In vivo 2-photon imaging of axonal regeneration and synaptic remodelling after laser-mediated micro lesions in the adult brain.
Canty, A. J, Huang, L., Jackson, J., Ruivo, L. Knott, G., Bohumil M., Nesarajan T., Little G., De Paola, V.
Society for Neuroscience (SfN) 2012 New Orleans, USA.
(Selected for oral presentation)
In vivo 2-photon imaging reveals increased axonal bouton dynamics in the aging mouse cortex.
Grillo, F., Song, S., Teles-Grilo Ruivo, L. M., Huang, L, Ge, G., Knott, G., Ferretti, V., Thompson, D., Little, G., De Paola, V.
Society for Neuroscience (SfN) 2012, New Orleans, USA.
A semi-automated program for axonal reconstructions from time-lapse 2-photon Images.
Yang, Z., Wang, Q., Gao, G., Li, X., Grillo, F., Ferretti,V., De Paola, V., Song, S.
Neuroinformatics 2012, Munich, Germany.
2011
2-photon imaging of axonal degeneration and synaptic turnover after laser-mediated micro lesions in the adult brain.
Canty, A. J., Jackson, J., Huang, L., De Paola, V.
In Vivo British Neuroscience Association (BNA) Meeting, 2011, Harrogate, United Kingdom.
(Selected for oral presentation)
2-photon in vivo imaging of laser-mediated microlesions in the adult brain.
Canty, A. J., Jackson, J., Nesarajah, C., Huang, L., De Paola, V.
The Institute of Photonic Sciences (IFCO) Light For Health Event, 30 – 31 May 2011, Barcelona, Spain.
2-photon in vivo imaging of cortical circuitry in the aged brain.
Grillo, F., De Paola, V.
Champalimaud Foundation Symposium, 2011, Lisbon, Portugal.
In vivo 2-photon imaging of bouton turnover after laser-mediated micro lesions in the adult brain.
Nesarajah, C., Canty, A., Jackson, J., Huang, L., De Paola, V.
NYAS Conference, 2011, New York, USA.
2010
In vivo 2-photon imaging of laser-mediated microlesions in the adult brain.
Canty, A. J., De Paola, V.
Australian Neuroscience Annual Meeting, 2010, Sydney, Australia.
(Selected for oral presentation)
In vivo 2-photon imaging of laser-mediated microlesions in the adult brain.
Canty, A. J., Huang, L., De Paola, V.
7th Federation of European Neuroscience Societies (FENS) Forum of European Neuroscience, 2 – 6 July 2010, Amsterdam, Netherlands.
In vivo 2-photon imaging of laser-mediated microlesions in the adult brain.
Canty, A. J., Huang, L., De Paola, V.
Structural Plasticity In The Mammalian Brain, 2010, HHMI Janelia Farm, USA.
2009
In vivo 2-photon imaging of laser-mediated microlesions in the adult brain.
Canty, A. J., De Paola, V.
British Neuroscience Association (BNA) Meeting, 2009, United Kingdom.
In vivo 2-photon imaging of axonal microlesions in the adult brain.
Canty, A. J., De Paola, V.
Spring School 2009 – “Regeneration and Plasticity of Neural Circuits”, 31 March – 02 April 2009, Cambridge Centre for Brain Repair, Cambridge, United Kingdom.
2008
In vivo imaging and computer-assisted analysis of axonal structure and dynamics.
De Paola, V.
Novel techniques in Neuroscience, 2009, Lund, Sweden.
2007 – 2003
2006
Cell-type specific experience-dependent structural plasticity of axonal branches and boutons in the adult neocortex.
De Paola, V., Song, S., Holtmaat, A., Wilbrecht, L., Knott, G., Caroni, P., Svoboda, K.
European Molecular Biology Organization (EMBO) Fellows Meeting, 2006, La Jolla, USA.
Cell-type specific experience-dependent structural plasticity of axonal branches and boutons in the adult neocortex.
De Paola, V., Song, S., Holtmaat, A., Wilbrecht, L., Knott, G., Caroni, P., Svoboda, K.
5th Federation of European Neuroscience Societies (FENS) Forum of European Neuroscience, 8 – 12 July 2006, Vienna, Austria.
2005
Long-term 2-photon imaging of cortical axons and their boutons in adult mice.
De Paola, V., Song, S., Holtmaat, A., Wilbrecht, L., Knott, G., Caroni, P., Svoboda, K.
CSHL Meeting – Imaging Neurons and Neural Activity: New Methods, New Results, 2005, Cold Spring Harbor, New York, USA.
Dendritic spine shape affects membrane-bound protein flux between the spine head and the dendritic shaft.
Hugel, S, De Paola, V., Caroni, P., Gähwiler, B. H., McKinney, R. A.
Society for Neuroscience Meeting, 2005, Washington, DC, USA.
2004
Long-term imaging of pre-synaptic terminals in the adult somatosensory cortex in vivo.
De Paola, V., Song, S., Holtmaat, A., Wilbrecht, L., Caroni, P., Svoboda, K.
Society for Neuroscience Meeting, 2004, San Diego, California, USA.
Activity-dependence of dendritic spine morphology and motility.
Hugel, S., Abegg, M., De Paola, V., Caroni, P., Gähwiler, B. H., McKinney, R.A.
Society for Neuroscience Meeting, 2004, San Diego, California, USA.
Dendritic spine morphology and motility are activity-dependent.
Hugel, S., Abegg, M., De Paola, V., Caroni, P., Gähwiler, B. H, McKinney, R. A.
4th Federation of European Neuroscience Societies (FENS) of European Neuroscience, 15 – 18 July 2004, Lisbon, Portugal.
In vivo imaging of cortical axon dynamics during early postnatal development reveals long-range growth and pruning prior to stable bouton formation.
Portera-Cailliau, C., De Paola, V., Caroni, P., Yuste,R., Svoboda, K.
Society for Neuroscience Meeting, 2004, San Diego, California, USA.
2003
AMPA Receptors regulate dynamic equilibrium of presynaptic terminals in the mature hippocampus.
De Paola, V., Caroni, P.
‘Brain in Motion’, EPFL, 2003, Lausanne, Switzerland.
High resolution visualization of synaptic morphology and dynamics in targeted-GFP transgenic mice.
De Paola, V., Sadhu, A., Pajusola, K., Pun, S., Xu, L., Arber, S., Caroni, P.
Basel Neuroscience Symposium: From Bench to Bedside, 2003, Basel, Switzerland.
Glutamate spillover triggers changes in synaptic connectivity.
Richards, D., De Paola, V., Caroni, P., Gähwiler, B., McKinney, R. A.
ZNZ Symposium, 2003, Neuroscience Center Zurich, Switzerland.
2002 – 1998
2002
High Resolution Visualization of Synaptic Morphology and Dynamics in Transgenic Mice Expressing GFP-Fusion Proteins In Single Neurons.
De Paola, V., Sadhu, A., Pajusola, K., Pun, S., Xu, L., Arber, S., McKinney, R. A., Caroni, P.
European Molecular Biology Organization (EMBO)/Friedrich Miescher Institute for Biomedical Research (FMI) Conference – Organizing the Brain: Genes, Neurons, and Circuits, 2002, Ascona, Switzerland.
Glutamate spillover triggers changes in synaptic connectivity.
Richards, D., De Paola, V., Caroni, P., Gähwiler, B., McKinney, R. A.
Society for Neuroscience Meeting, 2002, Orlando, Florida, USA.
2001
AMPA receptors regulate dynamic equilibrium of presynaptic terminals in the mature hippocampus.
De Paola, V., Caroni, P.
Swiss Societies for Experimental Biology (USGEB) Young Investigator Meeting, 2001, Lausanne, Switzerland.
2000
Transgenic mice expressing GFP fusion proteins in adult neurons of the central and peripheral nervous system.
De Paola, V., Caroni, P.
3rd Swiss Meeting on Muscle Research, 2000, Macolin, Switzerland.
1999
Transgenic mice expressing GFP fusion proteins in adult neurons of the central and peripheral nervous system.
De Paola, V., Caroni, P.
European Molecular Biology Organization (EMBO)/Friedrich Miescher Institute for Biomedical Research (FMI) Conference – Neuronal Circuits: From Molecules to Organisms, 1999, Ascona, Switzerland.
1998
Targeted-GFP expression in adult neurons of transgenic mice.
De Paola, V., Caroni, P.
2nd Swiss Meeting on Muscle Research, 1998, Macolin, Switzerland.