• Hippocampal neurons and nerve fibers labelled using Thy1-GFP transgenics

    Hippocampal neurons and nerve fibres labelled using Thy1-GFP transgenics

  • Imaging <em>in vivo</em> of an axon (red) and synaptophysin (green) through a cranial window on postnatal days (PND) 240-310

    Imaging in vivo of an axon (red) and synaptophysin (green) through a cranial window on postnatal days (PND) 240-310

  • Two-photon microscope images of the plasticity of adult cortical synapses <em>in vivo</em> on postnatal days (PND) 98-114

    Two-photon microscope imaging of the plasticity of adult cortical synapses in vivo on postnatal days (PND) 98-114

  • slider-home-CSC-retreat-ND-940x400

  • Microglia (green), brain cell nuclei (red)

    Microglia (green), brain cell nuclei (red)

  • slider-home-Melanie-cx-2-940x400

Welcome to the web site of the Synaptic Plasticity and Repair Group.

We study the structure and plasticity of brain circuits and their connections in both normal and disease settings, with a view to guide the development of better therapies for a number of cognitive and age-related disorders.

Latest News

05Sep

New paper on fully-automated method for detecting axonal synapses

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We have a new paper in PLoS One demonstrating a new, fully-automated, highly accurate approach for detecting axonal synapses (boutons).... Read More →
17Jul

Maria Tortora joins the Group

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Maria Tortora joins the Group on a 3 year Alzheimer’s Research UK (ARUK) PhD Scholarship to work on a new in... Read More →
05Jun

Shabana Khan joins the Group

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Shabana Khan joins the Group on a 3 year MRC postdoctoral fellowship to study the cellular and molecular mechanisms regulating... Read More →

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